Rani Therapeutics Holdings, Inc. Q4 2024 Earnings Call Transcript: Insights from Rani’s Executive Team

Rani Therapeutics Holdings, Inc. (NASDAQ: RANI ) Q4 2024 Earnings Conference Call

On March 31, 2025, at 4:30 PM ET, Rani Therapeutics Holdings, Inc. (RANI) held its Q4 2024 earnings conference call. The call was led by Kiki Patel of the Gilmartin Group, who served as the IR for the event. Rani’s CEO, Talat Imran, and CFO, Svai Sanford, were also in attendance to discuss the company’s financial results and corporate updates.

Company Participants

– Kiki Patel, IR, Gilmartin Group

– Talat Imran, CEO

– Svai Sanford, CFO

Conference Call Participants

  • – Annabel Samimy, Stifel
  • – Eka Gigauri, Oppenheimer
  • – Julian Harrison, BTIG
  • – Mitchell Kapoor, H.C. Wainwright
  • – Chad Yahn, Maxim Group
  • – Xinwei An, Canaccord Genuity
  • – John Vandermosten, Zacks

During the call, Rani Therapeutics reported its financial results for the fourth quarter and full year 2024. The company announced a net loss of $12.5 million for Q4 2024, which was a significant improvement from the net loss of $18.2 million in Q3 2024. For the full year 2024, Rani reported a net loss of $58.7 million, compared to $66.5 million in 2023.

Talat Imran, the CEO, discussed the company’s progress in developing its proprietary TPO (Transmucosal Pressure-Assisted) delivery system for insulin and other therapeutic proteins. He mentioned that the company had completed a successful Phase 1 clinical trial for its TPO insulin product and was planning to initiate a Phase 2 trial in the second half of 2025. Imran also shared that Rani was in discussions with several potential partners for licensing and collaborations.

Svai Sanford, the CFO, provided an update on the company’s financial position, stating that Rani had $32.5 million in cash and cash equivalents as of December 31, 2024. He also mentioned that the company had raised $25 million through a registered direct offering in February 2025.

Impact on Individual Investors

The earnings report and conference call provided some positive news for Rani Therapeutics investors. The significant improvement in the net loss for Q4 2024 and the successful completion of a Phase 1 clinical trial for the TPO insulin product were encouraging signs. However, the net loss for the full year 2024 was still high, and the company’s cash position remains a concern.

Impact on the World

The development of Rani Therapeutics’ TPO delivery system has the potential to revolutionize the way therapeutic proteins, such as insulin, are administered. If successful, this technology could make insulin injections a thing of the past, improving patient compliance and quality of life. Additionally, the TPO delivery system could be applied to other therapeutic proteins, expanding its market potential.

In conclusion, Rani Therapeutics’ Q4 2024 earnings conference call provided some promising updates on the company’s financial performance and progress in developing its TPO delivery system. While there are still challenges, the successful completion of a Phase 1 clinical trial and the potential market opportunity for this technology are exciting developments.

For individual investors, the net loss for the full year 2024 remains a concern, but the improvement in Q4 2024 and the potential for future partnerships and collaborations offer some optimism. For the world, the successful development and commercialization of Rani Therapeutics’ TPO delivery system could lead to a significant improvement in the way therapeutic proteins are administered, ultimately benefiting patients and healthcare systems.

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