Nanobiotix Unveils Exciting New Data from Two Phase 1 Studies on JNJ-1900-NBTXR3 at the European Lung Cancer Conference: A New Hope for Patients

Nanobiotix Announces Poster Presentations at the European Lung Cancer Conference

Paris, France and Cambridge, Massachusetts, March 20, 2025 – Nanobiotix, a pioneering biotechnology company specializing in nanoparticle-based therapeutic approaches, is pleased to announce that two Phase 1 studies on JNJ-1900 (NBTXR3) for patients with Non-Small Cell Lung Cancer (NSCLC) will be presented at the 2025 European Lung Cancer Conference (ELCC).

About Nanobiotix and JNJ-1900 (NBTXR3)

Nanobiotix is a late-clinical stage biotechnology company that has been pushing the boundaries of science to expand treatment possibilities for patients with cancer and other major diseases. Their lead product, JNJ-1900 (NBTXR3), is a proprietary nanoparticle-based platform technology designed to enhance the efficacy of various anti-cancer treatments. This innovative approach aims to improve the therapeutic index and safety profile of existing cancer therapies.

The Phase 1 Studies

The first study, titled “A Phase 1, Open-Label, Multicenter Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of NBTXR3 Monotherapy in Patients with Recurrent or Metastatic NSCLC,” will be presented on March 23, 2025. This study assessed the safety, pharmacokinetics, and preliminary efficacy of NBTXR3 monotherapy in patients with recurrent or metastatic NSCLC. The results showed that NBTXR3 was generally well-tolerated and demonstrated encouraging signs of anti-tumor activity.

The second study, titled “A Phase 1, Open-Label, Multicenter Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of NBTXR3 in Combination with Chemotherapy in Patients with Advanced NSCLC,” will be presented on March 24, 2025. This study evaluated the safety, pharmacokinetics, and preliminary efficacy of NBTXR3 in combination with chemotherapy in patients with advanced NSCLC. The data showed that NBTXR3 in combination with chemotherapy was generally well-tolerated and demonstrated an enhanced treatment effect compared to chemotherapy alone.

Impact on Patients

For patients with NSCLC, the results of these studies provide hope for a more effective and safer treatment option. NBTXR3, when used as a monotherapy or in combination with chemotherapy, showed promising signs of anti-tumor activity and an improved safety profile. These findings could lead to new treatment regimens for patients with NSCLC, ultimately improving their quality of life and potentially extending their survival.

Impact on the World

The advancements made by Nanobiotix in the development of JNJ-1900 (NBTXR3) have the potential to revolutionize the way we treat various types of cancer, including NSCLC. By enhancing the efficacy and safety of existing cancer therapies, NBTXR3 could lead to better treatment outcomes for millions of patients worldwide. Furthermore, this innovative approach may inspire further research in the field of nanoparticle-based therapeutics, paving the way for the discovery of new and effective treatments for various diseases.

Conclusion

Nanobiotix’s announcement of the poster presentations at the 2025 European Lung Cancer Conference marks an important step forward in the development of JNJ-1900 (NBTXR3) as a potential treatment for Non-Small Cell Lung Cancer. The promising results from these Phase 1 studies offer hope for patients with NSCLC, and the potential implications for the global cancer community are significant. As research continues, the impact of NBTXR3 on cancer treatment and patient outcomes remains an exciting prospect for the future.

  • Nanobiotix announces poster presentations at the European Lung Cancer Conference for two Phase 1 studies on JNJ-1900 (NBTXR3) for NSCLC.
  • The first study assessed the safety, pharmacokinetics, and preliminary efficacy of NBTXR3 monotherapy in patients with recurrent or metastatic NSCLC.
  • The second study evaluated the safety, pharmacokinetics, and preliminary efficacy of NBTXR3 in combination with chemotherapy in patients with advanced NSCLC.
  • Results showed that NBTXR3 was generally well-tolerated and demonstrated encouraging signs of anti-tumor activity when used as a monotherapy or in combination with chemotherapy.
  • These findings could lead to new treatment regimens for patients with NSCLC, ultimately improving their quality of life and potentially extending their survival.
  • The potential implications for the global cancer community are significant, as NBTXR3 could lead to better treatment outcomes for millions of patients worldwide.

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