New Study Reveals Sustained Low Disease Activity of Organon’s VTAMA™ Tapinarof Cream in Adults and Children with Atopic Dermatitis After Treatment-Free Interval in Phase 3 Trials

Organon’s ADORING 3 Study: Long-Term Effects of VTAMA® (tapinarof) Cream for Atopic Dermatitis

JERSEY CITY, N.J. – Organon, a renowned global healthcare company, recently unveiled intriguing findings from the Phase 3 ADORING 3 open-label, long-term extension study. This study centered around VTAMA® (tapinarof) cream, a potential solution for adults and children aged 2 years and above dealing with Atopic Dermatitis (AD), also recognized as eczema. The results shed light on the sustained effectiveness and safety of VTAMA® in managing AD.

Study Results:

The analysis revealed that patients who had achieved treatment success with VTAMA® during the initial study phase maintained mild disease activity throughout the long-term extension. Specifically, 53.6% of patients continued to experience a 75% reduction in the Eczema Area and Severity Index (EASI) score at week 104. Moreover, 76.5% of patients achieved and sustained an Investigator’s Global Assessment (IGA) score of clear or almost clear skin throughout the study.

Impact on Individuals:

For individuals living with AD, these findings could mean a significant improvement in their quality of life. Long-term symptom control can lead to reduced discomfort, less frequent flare-ups, and an overall sense of relief. Moreover, the potential for fewer topical applications and fewer prescription changes could save time and resources for both patients and healthcare providers.

  • Individuals may experience long-term symptom control and reduced discomfort
  • Fewer topical applications and prescription changes could save time and resources

Implications for the World:

The impact of these findings extends beyond individual patients. With an estimated 31.6 million Americans and over 160 million individuals worldwide living with AD, the potential for a long-term, effective treatment option could significantly improve the lives of millions. Furthermore, the economic burden of AD is substantial, with direct and indirect costs estimated to reach $11.2 billion annually in the United States alone. A treatment that reduces the frequency of flare-ups and the need for prescription changes could lead to substantial cost savings for the healthcare system.

  • Millions of individuals with AD could benefit from a long-term, effective treatment
  • Cost savings for the healthcare system due to reduced prescription changes and flare-ups

Conclusion:

The ADORING 3 study findings provide valuable insights into the long-term effectiveness and safety of VTAMA® (tapinarof) cream for managing atopic dermatitis. For individuals living with AD, these results could mean improved quality of life, fewer topical applications, and fewer prescription changes. On a larger scale, the potential for a long-term, effective treatment option could significantly impact the lives of millions and lead to substantial cost savings for the healthcare system. Continued research and clinical trials will provide further insight into the potential of VTAMA® as a game-changing solution for AD. Stay tuned for updates as the scientific community explores the possibilities.

Organon’s commitment to advancing women’s health and wellbeing is exemplified through the development of innovative treatments like VTAMA®. By focusing on the unique needs of patients, Organon aims to make a difference in the lives of those affected by AD and contribute to a healthier world.

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